Proteostasis and Disease From Basic Mechanisms to Clinics 2020 ORIGINAL PDF

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AUTHORS: Rosa Barrio James D. Sutherland Manuel S. Rodriguez
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Proteostasis and Disease From Basic Mechanisms to Clinics 2020 ORIGINAL PDF

This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology.

Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.

AUTHORS: Rosa Barrio James D. Sutherland Manuel S. Rodriguez

PAGES: 348

YEAR: 2020

PUBLICATION: Springer, Cham

LANGUAGE: English

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