- Series: Microbiology Monographs (Book 23)
- Hardcover: 416 pages
- Publisher: Springer; 2013 edition (August 14, 2012)
- Language: English
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Corynebacterium glutamicum: Biology and Biotechnology (Microbiology Monographs) 2013th Edition
by Nami Tatsumi (Editor)
Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins.
This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
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